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hla haplotype in Chinese

Pronunciation:
How to pronounce "hla haplotype""hla haplotype" in a sentence

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  • hla單倍型

Examples

  • At present , in an attempt to stimulate specific antitumor immunity , experimental models and clinical studies are currently evaluating the potent antigen - presenting capacity of dc combined with single or multiple tumor antigen epitopes . however , there are several problems in utilizing pulsing dc with synthetic immunodominant peptides from identified antigens . 1 ) the potential induction of tolerance ; 2 ) the need to determine the patient ' s hla haplotype , the limitation of therapy to patients whose tumors express defined specific tumor antigens in the context of the correct hla phenotype , the unavailability of peptides for all hla haplotypes ; 3 ) the lack of cd4 help cell - related epitopes for most antigens ; and 4 ) the ctl resulting from such protocols have a good in vitro capacity to kill peptide - pulsed target cells but only a modest capacity to kill tumor cells
    但是，學(xué)者們發(fā)現(xiàn)這一療法存在著如下的缺陷：?jiǎn)我籧tl表位抗原肽的應(yīng)用其抗腫瘤作用弱于多種腫瘤抗原的聯(lián)合應(yīng)用，且有誘導(dǎo)免疫耐受的潛在危險(xiǎn)，有時(shí)反而會(huì)促進(jìn)腫瘤的生長(zhǎng)；事先需對(duì)患者的hla單倍型進(jìn)行鑒定，以確定ctl表位與hla單倍型是否匹配，目前尚缺乏能與所有hla單倍型相匹配的ctl表位，從而限制了這一療法的應(yīng)用；這一療法所產(chǎn)生的ctl在體外能有效殺傷經(jīng)腫瘤抗原肽共孵育過(guò)的靶細(xì)胞，但對(duì)腫瘤細(xì)胞的殺傷能力較弱：這種l表位抗原肽缺乏cd4汀h細(xì)胞相關(guān)的表位，因此，不能誘導(dǎo)有效的th細(xì)胞免疫應(yīng)答。
What is the meaning of hla haplotype in Chinese and how to say hla haplotype in Chinese? hla haplotype Chinese meaning, hla haplotype的中文，hla haplotype的中文，hla haplotype的中文，translation, pronunciation, synonyms and example sentences are provided by ichacha.net.